部分发表论文列表

1.Dalong Hu, Zhiqiu Yin, Chao Yuan, Pan Yang, Chengqian Qian, Yi Wei, Si Zhang, Yuhui Wang, Jian Yuan, Meng Wang, Peter R. Reeves, Lihong Tu, Min Chen*, Di Huang*, Bin Liu*. Changing molecular epidemiology of Vibrio cholerae outbreaks in Shanghai, China. mSystems, 2019, 4(6). pii: e00561-19. 

2.Zhiqiu Yin, Chao Yuan, Yuhui Du, Pang Yang, Chengqian Qian, Yi Wei, Si Zhang, Di Huang*, Bin Liu*. Comparative genomic analysis of the Hafnia genus reveals an explicit evolutionary relationship between the species alvei and paralvei and provides insights into pathogenicity. BMC Genomics, 2019, 20(1):768. 

3.Cheng Wang*, Junhua Wang, Jian Yuan, Lingyan Jiang, Xiaolong Jiang, Bin Yang, Guang Zhao, Bin Liu, Di Huang*. Generation of Streptomyces hygroscopicus cell factories with enhanced ascomycin production by combined elicitation and pathway-engineering strategies. Biotechnology and Bioengineering, 2019, 116(12):3382-3395. 

4.Huanhuan Liu, Jing Zhang, Jian Yuan, Xiaolong Jiang, Lingyan Jiang, Guang Zhao, Di Huang*, Bin Liu*. Omics‑based analyses revealed metabolic responses of Clostridium acetobutylicum to lignocellulose‑derived inhibitors furfural, formic acid and phenol stress for butanol fermentation. Biotechnology for Biofuels, 2019, 12:101. 

5.Linbo Sun#, Di Huang#, Lin Zhu#, Bingling Zhang, Chenchen Peng, Ting Ma, Xin Deng, Junli Wu, Wei Wang*. Novel thermostable enzymes from Geobacillus thermoglucosidasius W-2 for high-efficient nitroalkane removal under aerobic and anaerobic conditions. Bioresource Technology, 2019, 278:73-81.

6.Chenchen Peng#, Di Huang#, Yukun Shi, Bingling Zhang, Linbo Sun, Mingchang Li, Xin Deng,Wei Wang*.Comparative transcriptomic analysis revealed the key pathways responsible for organic sulfur removal by thermophilic bacterium Geobacillus thermoglucosidasius W-2. Science of the Total Environment, 2019, 676: 639–650.

7.Di Huang, Kexin Yang, Jia Liu, Yingying Xu, Yuanyuan Wang, Ru Wang, Bin Liu*, Lu Feng*, Metabolic engineering of Escherichia coli for the production of 2′-fucosyllactose and 3-fucosyllactose through modular pathway enhancement. Metabolic Engineering, 2017, 41:23-38.

8.Di Huang*, Ru Wang, Wenjie Du, Guanyi Wang, Menglei Xia, Activation of glycerol metabolic pathway by evolutionary engineering of Rhizopus oryzae to strengthen the fumaric acid biosynthesis from crude glycerol. Bioresource Technology, 2015, 196:263-272.

9.Di Huang, Jia Liu, Yanfei Qi, Kexin Yang, Yingying Xu, Lu Feng*, Synergistic hydrolysis of xylan using novel xylanases, β-xylosidases, and an α-L-arabinofuranosidase from Geobacillus thermodenitrificans NG80-2. Applied Microbiology and Biotechnology, 2017, 101(15):6023-6037.

10.Di Huang#, Yongpeng Yao#, Hang Zhang, Zhu Mei, Ru Wang, Lu Feng, Bin Liu*, Directed optimization of a newly identified squalene synthase from Mortierella alpine based on sequence truncation and site-directed mutagenesis. Journal of Industrial Microbiology and Biotechnology, 2015, 42(10):1341-1352. 

11.Huanhuan Liu#, Di Huang#, Lina Jin#, Cheng Wang, Shaoxiong Liang, Jianping Wen*, Integrating multi-omics analyses of Nonomuraea dietziae to reveal the role of soybean oil in [(4′-OH)MeLeu]4-CsA overproduction. Microbial Cell Factories, 2017, 16:120. 

12.Huanhuan Liu#, Di Huang#, Jianping Wen*, Integrated intracellular metabolic profiling and pathway analysis approaches reveal complex metabolic regulation by Clostridium acetobutylicum. Microbial Cell Factories, 2016, 15:36.

13.Guanyi Wang#, Di Huang#, Yong Li, Jianping Wen*, Xiaoqiang Jia, A metabolic-based approach to improve xylose utilization for fumaric acid production from acid pretreated wheat bran by Rhizopus oryzae. Bioresource Technology, 2015, 180:119-127.

14.Wenjie Du#, Di Huang#*, Menglei Xia, Jianping Wen*, Ming Huang, Improved FK506 production by the precursors and product-tolerant mutant of Streptomyces tsukubaensis based on genome shuffling and dynamic fed-batch strategies. Journal of Industrial Microbiology and Biotechnology, 2014, 41(7):1131-1143.

15.Jun Wang#, Huanhuan Liu#, Di Huang#, Lina Jin, Cheng Wang, Jianping Wen*, Comparative proteomic and metabolomic analysis of Streptomyces tsukubaensis reveals the metabolic mechanism of FK506 overproduction by feeding soybean oil. Applied Microbiology and Biotechnology, 2017, 101(6):2447-2465.

16.Cheng Wang*#, Di Huang#, Shaoxiong Liang. Identification and metabolomic analysis of chemical elicitors for tacrolimus accumulation in Streptomyces tsukubaensis. Applied Microbiology and Biotechnology, 2018, 102:7541-7553.

17.Yuhui Du, Huiying Li, Zhiqiu Yin, Antoni Rozalski, Agnieszka Torzewska, Pan Yang, Chengqian Qian, Tingting Xu, Hengchun Cao, Pan Wu, Lingyan Jiang, Xi Guo, Di Huang⁎, Bin Liu*. Development of a molecular serotyping scheme and a multiplexed luminex-based array for Providencia. Journal of Microbiological Methods, 2018, 153:14-23.

18.Di Huang, Shanshan Li, Menglei Xia, Jianping Wen*, Xiaoqiang Jia. Genome-scale metabolic network guided engineering of Streptomyces tsukubaensis for FK506 production improvement. Microbial Cell Factories, 2013, 12:52.

19.Di Huang, Menglei Xia, Shanshan Li, Jianping Wen*, Xiaoqiang Jia. Enhancement of FK506 production by engineering secondary pathways of Streptomyces tsukubaensis and exogenous feeding strategies. Journal of Industrial Microbiology and Biotechnology, 2013, 40(9):1023-1037.

20.Di Huang, Jianping Wen*, Guoying Wang, Guanghai Yu, Xiaoqiang Jia and Yunlin Chen. In silico aided metabolic engineering of Streptomyces roseosporus for daptomycin yield improvement. Applied Microbiology and Biotechnology, 2012, 94(3):637-649.

21.Di Huang, Xiaoqiang Jia, Jianping Wen*, Guoying Wang, Guanghai Yu, Qinggele Caiyin and Yunlin Chen. Metabolic flux analysis and principal nodes identification for daptomycin production improvement by Streptomyces roseosporus. Applied Biochemistry and Biotechnology, 2011, 165(7-8):1725-1739.

22.Guanyi Wang#, Di Huang#, Haishan Qi, Jianping Wen*, Xiaoqiang Jia. Rational medium optimization based on comparative metabolic profiling analysis to improve fumaric acid production. Bioresource Technology, 2013, 137:1-8. 

23.Menglei Xia#, Di Huang#, Shanshan Li, Jianping Wen*, Xiaoqiang Jia, Yunlin Chen. Enhanced FK506 production in Streptomyces tsukubaensis by rational feeding strategies based on comparative metabolic profiling analysis. Biotechnology and Bioengineering, 2013, 110(10):2717-2730.