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个人概况：
2014年博士毕业于南开大学细胞生物学专业。2014至2020年于耶鲁大学/霍华德休斯医学研究所从事博士后工作，并于2015至2018年获得人类前沿科学计划（HFSP）长期奖学金资助。2020年回到南开大学任职。主要从事细胞器互作及动态变化的分子机制和功能的研究；已在细胞质膜的脂质稳态调控以及内质网膜融合的分子基础等领域取得了一系列突破进展；以第一作者或共同第一作者发表论文4篇，包括1篇NatureChemical Biology、1篇EMBOJournal、2篇PNAS；受邀在Methodsin Molecular Biology上撰写著作1章。其它参与的工作也发表在Science、NatureCell Biology、PNAS、Protein& Cell等高水平杂志上。
研究方向：
1.细胞器间相互作用的分子机制和生理意义；
2.细胞器动态变化的分子基础。
招生方向：生物膜结构与功能
1.Ye, J., Bian, X., Lim,J., & Medzhitov, R. Adiponectinand related C1q/TNF-related proteins bind selectively to anionic phospholipidsand sphingolipids. PNAS,117(29), 17381-17388. (2020).
2.Bian, X., & De Camilli, P. In vitro assays to measure the membrane tethering and lipid transport activities of the extended synaptotagmins. Methods in Molecular Biology (Humana Press), 1949, 201-212. (2019).
3.Guillén-Samander, A., Bian, X.,& De Camilli, P. PDZD8 mediates a Rab7 dependentinteraction of the ER with late endosomes and lysosomes. PNAS, 116(45),22619-22623. (2019).
4.Bian, X.#, Zhang, Z.#, Xiong Q., De Camilli, P., & Lin, C. A programmable DNA-origami platform for studying lipid transfer between bilayers. Nature Chemical Biology, 15(8), 830-837. (2019). Recommended in F1000Prime. (#共同第一作者).
5.Sun, E.,Guillén-Samander, A., Bian, X., Wu, Y., Cai, Y.,Messa, M., & De Camilli, P. Lipid transporter TMEM24/C2CD2L is a Ca2+-regulated component of ER-plasmamembrane contacts in mammalian neurons. PNAS, 116(12), 5775-5784. (2019).
6.Milovanovic, D.,Wu, Y., Bian, X.,& De Camilli, P. A liquid phase of synapsin and lipid vesicles. Science, 361(6402),604-607. (2018).
7.Bian, X., Saheki, Y., & De Camilli, P. Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport. EMBO Journal, 37(2), 219-234. (2018).
8.Saheki, Y., Bian, X.#, Schauder, C.M.#, Sawaki, Y., Surma,M.A., Klose, C., Pincet, F.,Reinisch, K.M., & De Camilli, P. Control of plasma membrane lipidhomeostasis by the extended synaptotagmins. Nature Cell Biology, 18(5), 504-515. (2016). (# 共同第二作者).
9.Liu, T., Bian, X., Romano, F., Shemesh, T., Rapoport, T., & Hu, J. Cisand trans interactions between atlastinmolecules during membrane fusion. PNAS, 112(15), E1851-E1860.(2015).
10.Wu, F.#, Hu, X.#, Bian, X., Liu,X., & Hu, J. Comparison of human and Drosophila atlastin GTPases. Protein & Cell, 6(2), 139-146.(2015). (# 共同第一作者).
11.Liu, T.#, Bian, X.#, Sun, S., Hu, X., Klemm, R., Prinz, W., Rapoport, T.,& Hu, J. Lipid interaction of the C terminus andassociation of the transmembrane segments facilitate atlastin-mediated homotypic endoplasmic reticulumfusion. PNAS,109(32), E2146-E2154.(2012). (# 共同第一作者).
12.Bian, X.#, Liu, T.#, Klemm, R.#, Zhang, M., Sun, S., Sui, X., Liu, X., Rapoport, T., & Hu, J. Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes. PNAS, 108(10), 2976-3981. (2011). Recommended in F1000Prime. (# 共同第一作者).
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