个人信息
Personal Information
联系方式
Contact Information
个人简介
Personal Profile
郭玮炜研究员2003年于吉林大学化学学院获得理学学士学位，2010年于中科院长春应化所获得理学博士学位，师从汪尔康院士，2011年至2015年于以色列耶路撒冷希伯来大学从事博士后研究，合作导师Itamar Willner教授，2015年11月入职南开大学化学学院担任特聘研究员。郭玮炜研究员致力于发展智能的生化分析方法和传感装置，集中于研究具备多功能可编码的DNA传感材料包括DNA水凝胶与纳米结构等传感材料及结合纳米簇、量子点和功能二维结构等的复合功能传感材料的设计、调控及相关基础科学问题，和建立针对不同类型生化分析目标的分离检测新原理与新方法，进而开发智能的生化分析试纸与芯片、穿戴式生化传感器和植入式诊疗一体化系统，目前已经取得了一系列创新研究成果，在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Adv. Mater.等相关领域国际顶级或高水平期刊发表论文47篇，总引用次数超过3300次，H因子为33，其中最高单篇他引超过400次，多篇论文入选ESI高被引论文。此外，担任中文核心期刊《分析试验室》编委（第五届），担任《分析化学》、《应用化学》、《Journal of Analysis and Testing》和《SmartMat》青年编委。
目前，已先后主持国家自然科学基金青年与面上项目、天津市自然科学基金重点项目以及南开大学百青项目等多项，并于2016年入选天津市海外高层次人才青年项目，于2019年入选第四批国家“万人计划”青年拔尖人才项目。
近期学术成果：
(1) Chunyan Wang, Cuiyan Han, Xiaoxue Du, Weiwei Guo, Versatile CRISPR-Cas12a-Based Biosensing Platform Modulated with Programmable Entropy-Driven Dynamic DNA Networks, Anal. Chem. 2021, 93, 12881−12888.
(2) Xiaoxue Du, Yanhui Bi, Pingping He, Chunyan Wang, Weiwei Guo*, Hierarchically Structured DNA-Based Hydrogels Exhibiting Enhanced Enzyme-Responsive and Mechanical Properties, Adv. Funct. Mater. 2020, 30, 2006305.
(3) Yanhui Bi, Xiaoxue Du, Pingping He, Chunyan Wang, Chang Liu, Weiwei Guo*, Smart Bilayer Polyacrylamide/DNA Hybrid Hydrogel Film Actuators Exhibiting Programmable Responsive and Reversible Macroscopic Shape Deformations, Small 2020, 16, 1906998.
(4) Cuiyan Han, Weiwei Guo*, Fluorescent Noble Metal Nanoclusters Loaded Protein Hydrogel Exhibiting Anti-Biofouling and Self-Healing Properties for Electrochemiluminescence Biosensing Applications, Small 2020, 16, 2002621.
(5) Fengyun Li, Danya Lyu, Shuo Liu, Weiwei Guo*, DNA Hydrogels and Microgels for Biosensing and Biomedical Applications, Adv. Mater. 2020, 32, 1806538.
(6) Chunyan Wang, Fengyun Li, Yanhui Bi, Weiwei Guo*, Reversible Modulation of Two-Dimensional Photonic Crystals with a Responsive Shape-Memory DNA Hydrogel Film, Adv. Mater. Interfaces 2019, 6, 1900556.
(7) Danya Lyu, Jing Li, Xiaowen Wang, Weiwei Guo*, and Erkang Wang*, Cationic Polyelectrolyte Modified Fluorescent DNA-Silver Nanoclusters for Rapid Bioimaging with Enhanced Emission and Higher Stability, Anal. Chem. 2019, 91, 2050-2057.
(8) Yanhui Bi, Cuiyan Han, Weiwei Guo*, Smart DNA Hydrogels for Biosensing Applications, Sci. Sin. Chim. 2019, 49: 766-775.
(9) Fengyun Li, Qi Gao, Mingjie Yang, Weiwei Guo*, Regulation of Catalytic DNA Activities with Thermosensitive Gold Nanoparticle Surfaces, Langmuir 2018, 34, 14932-14939.
(10) Shuo Liu, Weiwei Guo*, Anti-Biofouling and Healable Materials: Preparation, Mechanisms, and Biomedical Applications, Adv. Funct. Mater. 2018, 28, 1800596.
(11) Jingrun Ran, Weiwei Guo*, Hailong Wang, Bicheng Zhu, Jiaguo Yu, Shi-Zhang Qiao*, Metal-Free 2D/2D Phosphorene/g-C3N4 Van der Waals Heterojunction for Highly Enhanced Visible-Light Photocatalytic H2 Production, Adv. Mater. 2018, 30, 1800128 (ESI高被引论文).
(12) Shanshan Chen, Danya Lyu, Tao Ling, Weiwei Guo*, Reversible Modulation of CsPbBr3 Perovskite Nanocrystal/gold Nanoparticle Heterostructures, Chem. Commun. 2018, 54, 4605--4608.
(13) Jingtao Wang(#), Pingping Chen(#), Benbing Shi, Weiwei Guo*, Mietek Jaroniec, Shi-Zhang Qiao*, Regularly Channeled Lamellar Membrane for Unparalleled Water and Organics Permeation, Angew. Chem. Int. Ed. 2018, 57, 6814-6818 (封面文章).
(14) Fengyun Li, Chunyan Wang, and Weiwei Guo*, Multifunctional Poly-N-Isopropylacrylamide/DNAzyme Microgels as Highly Efficient and Recyclable Catalysts for Biosensing, Adv. Funct. Mater. 2018, 28, 1705876.
(15) Danya Lyu, Shanshan Chen, Weiwei Guo*, Liposome Crosslinked Polyacrylamide/DNA Hydrogel: a Smart Controlled-Release System for Small Molecular Payloads, Small 2018, 14, 1704039.
(16) Weiwei Guo(#), Chun-Hua Lu(#), Ron Orbach, Fuan Wang, Xiu-Juan Qi, Alessandro Cecconello, Dror Seliktar, Itamar, Willner*, pH-Stimulated DNA Hydrogels Exhibiting Shape-Memory Properties, Adv. Mater. 2015, 27, 73-78.
(17) Chun-hua Lu(#), Weiwei Guo (#), Yuwei Hu, Xiu-Juan Qi, Itamar Willner*, Multi-Triggered Shape-Memory Acrylamide-DNA Hydrogels, J. Am. Chem. Soc. 2015, 137, 15723–15731.
(18) Weiwei Guo(#), Chun-Hua Lu(#), Xiu-Juan Qi, Ron Orbach, Michael Fadeev, Huang-Hao Yang, Itamar Willner*, Switchable Bifunctional Stimuli-Triggered Poly-N-Isopropylacrylamide/DNA Hydrogels, Angew. Chem. Int. Ed. 2014, 53, 10134 –10138. (VIP文章)
(19) Weiwei Guo, Jipei Yuan, Qingzhe Dong, Erkang Wang*, Highly sequence-dependent formation of fluorescent silver nanoclusters in hybridized DNA duplexes for single nucleotide mutation identification, J. Am. Chem. Soc. 2010, 132, 932-934. (ESI 高被引论文)
(20) Chun-hua Lu(#), Weiwei Guo (#), Xiu-Juan Qi, Avner Neubauer, Yossi Paltiel, Itamar, Willner*, Hemin-G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline, Chem. Sci. 2015, 6, 6659-6664.
(21) Weiwei Guo(#), Ron Orbach(#), Iris Mironi-Harpaz, Dror Seliktar, Itamar Willner*, Fluorescent DNA hydrogels composed of nucleic Acid-stabilized silver nanoclusters, Small 2013, 9, 3748-3752.
(22) Weiwei Guo(#), Xiu-Juan Qi(#), Ron Orbach, Chun-hua Lu, Lina Freage, Iris Mironi-Harpaz, Dror Seliktar, Huang-Hao Yang, Itamar Willner*, Chem. Commun. 2014, 50, 4065-4068.
(23) Ron Orbach(#), Weiwei Guo(#), Fuan Wang, Oleg Lioubashevski, Itamar Willner*, Self-Assembly of Luminescent Ag Nanocluster-Functionalized Nanowires, Langmuir 2013, 29, 13066-13071.
(24) Weiwei Guo, Jipei Yuan, Erkang Wang*, Oligonucleotide-stabilized Ag nanoclusters as novel fluorescence probes for the highly selective and sensitive determination of Hg2+ ion, Chem. Commun. 2009, 3395-3397. (ESI 高被引论文)
*: Corresponding author; #: equal first author
文件上传中...
