个人信息
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个人简介
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工作经历:
2019.01 - 至今: 南开大学 特聘研究员 博士生导师
2014.09 - 2018.12: 美国德克萨斯大学西南医学中心 博士后 合作导师: Daniel J. Siegwart
教育经历:
2009.09 - 2014.07: 中科院上海有机化学研究所 硕博在读 导师: 唐勇院士, 谢作伟院士
2005.09 - 2009.06: 郑州大学 学士 导师: 崔秀灵教授
代表性研究成果:
(1) Chen, Z., Yang, Y., Qiu, X., Zhou, H., Wang, R., Xiong, H.* Crown-Like Biodegradable Lipids Enable Lung-Selective mRNA Delivery and Dual-Modal Tumor Imaging In Vivo. Journal of the American Chemical Society, 2024, 146, 34209–34220.
(2) Chen, Z., Tian, Y., Yang, J., Wu, F., Liu, S., Cao, W., Xu, W., Hu, T., Siegwart, D. J., Xiong, H.* Modular Design of Biodegradable Ionizable Lipids for Improved mRNA Delivery and Precise Cancer Metastasis Delineation In Vivo. Journal of the American Chemical Society, 2023, 145, 24302–24314.
(3) Zhu, Y., Wu, P., Liu, S., Yang, J., Wu, F., Cao, W., Yang, Y., Zheng, B., Xiong, H.* Electron-Withdrawing Substituents Allow Boosted NIR-II Fluorescence in J-Type Aggregates for Bioimaging and Information Encryption. Angewandte Chemie International Edition, 2023, 62, e202313166.
(4) Tian, Y., Chen, Z., Liu, S., Wu, F., Cao, W., Pang, D.-W.*, Xiong, H.* “Dual-Key-and-Lock” NIR-II NSCyanines Enable High-Contrast Activatable Phototheranostics in Extrahepatic Diseases. Angewandte Chemie International Edition, 2023, 62, e202309768.
(5) Zhu, Y., Wu, F., Zheng, B., Yang, Y., Yang, J., Xiong, H.* Electron-Withdrawing Substituents Enhance Type-I PDT and NIR-II Fluorescence of BODIPY J-aggregates for Bioimaging and Cancer Therapy. Nano Letters, 2024, 24, 8287–8295.
(6) Liu, S., Xu, W., Li, X., Pang, D.-W., Xiong, H.* BOIMPY-based NIR-II Fluorophore with High Brightness and Long Absorption beyond 1000 nm for In Vivo Bioimaging: Synergistic Steric Regulation Strategy. ACS Nano, 2022, 16, 17424–17434.
(7) Wu, P., Zhu, Y., Liu, S., Xiong, H.* Modular Design of High-Brightness pH-Activatable Near-Infrared BODIPY Probes for Noninvasive Fluorescence Detection of Deep-Seated Early Breast Cancer Bone Metastasis: Remarkable Axial Substituent Effect on Performance. ACS Central Science, 2021, 7, 2039–2048.
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