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药物化学生物学国家重点实验室研究员，博士生导师，天津市细胞生物学会理事，Stem Cells International特刊客座主编。2013年从新加坡国立大学获得博士学位，2013年至2015年在新加坡基因组研究院从事博士后工作。 主要研究胚胎干细胞中转座子的功能与表观调控。利用功能基因组学方法如高通量基因筛选、高通量测序、表观遗传学技术、生物信息学大数据分析等手段研究干细胞与遗传疾病中关键转座子及重复序列的表达调控模式与功能，获得多项国家级科学基金资助，以通讯作者/第一作者在Nucleic Acids Research、Nature Cell Biology、 Nature Structural & Molecular Biology等杂志发表文章。
1. Chen,F.#, Zhang, W. #, Xie, D. #, Gao, T., Dong, Z.and Lu, X*. (2020) Histone chaperoneFACT represses retrotransposon MERVL and MERVL-derived cryptic promoters. Nucleic acids research, 48, 10211-10225.
2. Zhang,W. #, Chen, F. #, Chen, R. #, Xie, D., Yang,J., Zhao, X., Guo, R., Zhang, Y., Shen, Y., Goke, J. Liu, L.*, Lu, X.*(2019) Zscan4c activatesendogenous retrovirus MERVL and cleavage embryo genes. Nucleic acids research, 47,8485-8501.
3. Fu,E. #, Shen, J. #, Dong, Z., Zhang, W., Zhang, Y., Chen,F., Cheng, Z., Zhao, X., Shuai, L. and Lu,X.* (2019) Histone demethylase Kdm2a regulates germ cell genes andendogenous retroviruses in embryonic stem cells. Epigenomics, 11,751-766.
4. Gao,T., Chen, F., Zhang, W., Zhao, X., Hu, X. and Lu, X.* (2021) Nsd2 Represses Endogenous Retrovirus MERVL inEmbryonic Stem Cells. Stem Cells Int,2021, 6663960.
5. Chen,F., Zhang, M., Feng, X., Li, X., Sun, H. and Lu, X.* (2021) Discovery of a Novel Long Noncoding RNA Lx8-SINE B2as a Marker of Pluripotency. Stem CellsInt, 2021, 6657597.
6. Chen,F., Ji, J., Shen, J. and Lu, X.*(2017) When Long Noncoding RNAs Meet Genome Editing in Pluripotent Stem Cells. Stem Cells Int, 2017, 3250624.
7. Lu, X., Sachs, F., Ramsay, L., Jacques,P.E., Goke, J., Bourque, G.* and Ng, H.H.*(2014) The retrovirus HERVH is a longnoncoding RNA required for human embryonic stem cell identity. Nature structural & molecular biology,21, 423-425.
8. Lu, X. #, Goke, J. #,Sachs, F., Jacques, P.E., Liang, H., Feng, B., Bourque, G., Bubulya, P.A. andNg, H.H.* (2013) SON connects thesplicing-regulatory network with pluripotency in human embryonic stem cells. Nature cell biology, 15, 1141-1152.
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