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个人概况：
2022年：南开大学“百名青年学科带头人”；2021年：国家自然科学基金委“优秀青年基金”；2017年：天津市首批“青年人才托举工程”；2016年：天津市“131创新型人才计划”；2014年：天津市自然科学一等奖。
2004-2008，天津大学材料学院，材料科学与工程工学学士。 2008-2013，南开大学生命科学学院，高分子化学与物理博士。
2013-2017，南开大学药物化学生物学国家重点实验室，助理研究员。2017-2022，南开大学药物化学生物学国家重点实验室，副研究员。2019-2020，加州大学洛杉矶分校生物工程系，访问学者。 2022-至今，南开大学生命科学学院，研究员（与药化生国重双聘）。
2013年入职南开大学药物化学生物学国家重点实验室，一直在“多肽自组装生物材料”研究领域开展工作，利用多学科（材料学、化学、生物学等）交叉的优势，围绕多肽自组装生物材料的研发及其在缺血性疾病和癌症诊疗方面的应用开展研究。共发表SCI收录论文50余篇，以通讯/第一作者发表论文37篇，包括J. Am. Chem. Soc.，Adv. Mater.，Angew. Chem. Int. Ed.，Chem. Soc. Rev.，Adv. Funct. Mater.，Adv. Sci.，Nano. Lett.等。申请中国发明专利10项，授权5项，转让2项。申请美国发明专利1项。先后主持国家自然科学基金优青和面上项目在内的科研项目9项。中国医药生物技术协会纳米生物技术分会委员，天津市交叉科学学会理事，天津市药理学会实验药理专委会委员。《Exploration》杂志青年编委；Nano Letters、ACS Nano、Chemical Engineering Journal、Biomaterials、Acta Biomaterialia等国际刊物审稿人。
研究方向：
1.活性多肽自组装治疗缺血性疾病；
2.多肽自组装纳米药物用于癌症诊疗。
招生方向：生物材料与组织工程
1. 国家自然科学基金委员会，面上项目，自组装多肽用于血脑屏障穿越以及脑部药物递送的研究，2024.01-2027.12，65万，主持，在研。
2. 国家重点研发计划，呼吸道病毒疫苗新型纳米佐剂的构建及增效机制研究，2022.12-2025.11，390万，项目骨干，在研。
3. 国家自然科学基金委员会，优秀青年基金项目，多肽可控自组装用于缺血性疾病治疗，2022.01-2024.12，200万，主持，在研。
4. 国家重点研发计划，生物催化剂固定化及催化过程强化与调控，2021.07-2025.06，594万，子课题骨干，在研。
5. 国家自然科学基金委员会，面上项目，自组装调控的多肽折叠及其在生长因子活性模拟中的应用，2020.01-2023.12，69万，主持，结题。
6. 天津市科协，天津市青年人才托举工程第一批，2018.04-2021.03，45万，主持，结题。
7. 国家自然科学基金委员会，面上项目，具有细胞核聚集效应的双抗癌纳米药物的制备及药效评价，2018.01-2021.12，70万，主持，结题。
8. 国家自然科学基金委员会，青年项目，细菌表面诱导多肽自组装用于细菌的检测及生长抑制，2015.01-2017.12，25万，主持，结题。
9. 天津市应用基础与前沿技术研究计划，青年项目，基于顺铂等抗癌药物的小分子水凝胶的构建及应用研究，2015.04-2018.03，8万，主持，结题。
1. Sun, X.; Ren, H.; Cui,Y.-C.; Liu, Q.; Li, J.* and Gao, J.*, Surface-inducedself-assembly of peptides turns superhydrophobic surface of electrospun fibrousinto superhydrophilic one. ColloidsSurf. B2025, 245, 114350. (IF=5.4)
2. Sun, X.; Li, D.; Lv, Y.; Zhang, M.; Qiao, D.; Zhang, Z.; Ren, H.; Zhang,Y.; Yang, Z.* and Gao, J.*, Nanomaterials for the Diagnosis andTreatment of Triple-Negative Breast Cancer. WIREs Nanomed. Nanobiotechnol. 2024, 16 (6), e2019. (IF=6.9)
3. Cai,X.; Zhang, M.; Zou, J.; Wang, L.; Zhan,Y.; Li, D.; Jiang, T.; Alim, N.; Liu, Z.; Yang, J.; Liu, N.; Liu, T.; Sun, P.;Ding, X.; Zhang, B.; Liu, Z.; Wang, X.; Liang, R.; Cai, J.; Gao, J.*;Cao, J.*;Wang, S.*,A novel self-assembling peptide nanofiber hydrogel with glucagon-like peptide-1functionality enhances islet survival to improve islet transplantation outcomein diabetes treatment. J. Nanobiotechnol.2024, 22 (1), 792. (IF=10.6)
4. Ma,H.; Xu, L.; Wu, S.; Wang, S.; Li, J.; Ai, S.; Yang, Z.; Mo, R.; Lin, L.; Li,Y.; Wang, S.;Gao J.*; Li C.* and Kong D.*,Supragel-mediated efficient generation of pancreatic progenitor clusters andfunctional glucose-responsive islet-like clusters. Bioact. Mater. 2024, 41, 1-14. (IF=18.0)
5. Zhang,X.; Zhang, B.; Zhang, Y.; Ding, Y.; Zhang, Z.; Liu, Q.; Yang, Z.; Wang, L.* andGao, J.*, Copper-induced Supramolecular Peptide Assemblies forMulti-pathway Cell Death and Tumor Inhibition. Angew. Chem. Int. Ed. 2024, e202406602. (IF=16.6)
6. Zheng, D#; Guo J.#, Liu J.; Jin, Y.; Qi, C.; Li, X.; Shi, K.; Ding, Y.; Xie,L.; Wang, L.; Hu, Z.; Yang, Z.; Liu, Q.; Ning, W.* and Gao, J.*, SupramolecularNanofibers Ameliorate Bleomycin-Induced Pulmonary Fibrosis by RestoringAutophagy. Adv. Sci. 2024, 2401327. (IF=15.1)
7. Cai,X.#; Cao, J.#; Wang, L.; Zou, J.; Li, R.; Sun, P.; Ding,X.; Zhang, B.; Liu, Z.; Pei, X.; Yang, J.; Zhan, Y.; Liu, N.; Liu, T.; Liang,R.*; Gao J.*; Wang S.*,Liraglutide Protects Pancreatic Islet From Ischemic Injury by ReducingOxidative Stress and Activating Akt Signaling During Cold Preservation toImprove Islet Transplantation Outcomes. Transplantation 2024, 108 (8), e156-e169. (IF=5.3)
8. Zhang, X.; Wang, J.; Zhang, Y.; Yang, Z.; Gao,J.*; Gu, Z.*, Synthesizing biomaterials in living organisms. Chem. Soc. Rev. 2023, 52 (23), 8126-8164. (IF=46.2)
9. Chen,Y.; Li, W.; Wang, Z.; Yu, Y.; Li, J.; Ding, Y.; Hu, Z.; Liu, Q.; Yang, Z.*; Gao,J.*, A Transformable Supramolecular Bispecific Cell Engager for AugmentingNatural Killer and T Cell-Based Cancer Immunotherapy. Adv. Mater. 2023, 36(3), 2306736. (IF=29.4)
10. Li,X.#; Zhang, Y.#; Wang, Y.; Chen, Y.; Xu, T.; Wang, L.*; Gao,J.*; Yang, Z.*, A blood-brain barrier crossing peptide. Sci. China. Mater. 2023, 66 (8),3327-3336. (IF=8.1)
11. Yang,C.; Mu, G.; Zhang, Y.; Gao, Y.; Zhang, W.; Liu, J.; Zhang, W.; Li, P.; Yang,L.; Yang, Z.; Gao, J.*; Liu, J.*, Supramolecular Nitric Oxide Depot forHypoxic Tumor Vessel Normalization and Radiosensitization. Adv. Mater. 2022, 34 (37), 2202625. (IF=29.4)
12. Li,X.; Yu, Z.; Jiang, S.; Dai, X.; Wang, G.; Wang, Y.; Yang, Z.; Gao, J.*;Zou, H.*, An amelogenin-based peptide hydrogel promoted the odontogenicdifferentiation of human dental pulp cells. Regen. Biomater. 2022, 9, rbac039. (IF=6.7)
13. Zhang,Y.; Yu, Y.; Gao, J.*, Supramolecular Nanomedicines of In-SituSelf-Assembling Peptides. Front. Chem. 2022,10, 815551. (IF=5.5)
14. Li,X.; Wang, Y.; Zhang, Y.; Yang, Z.; Gao, J.*; Shi, Y.*, Enzyme InstructedSelf-assembly (EISA) Assists the Self-assembly and Hydrogelation of HydrophobicPeptides. J. Mater. Chem. B. 2022,10 (17), 3242-3247. (IF=7)
15. Ai,S.; Li, H.; Zheng, H.; Liu, J.; Gao, J.*; Liu, J.*; Chen, Q.*; Yang,Z.*, A SupraGel for efficient production of cell spheroids. Sci. ChinaMater.2022, 65 (6), 1655-1661. (IF=8.1)
16. Zheng,D.; Liu, J.; Ding, Y.; Xie, L.; Zhang, Y.; Chen, Y.; Peng, R.; Cai, M.; Wang,L.; Wang, H.*; Gao, J.*; Yang, Z.*, Tandem molecular self-assembly forselective lung cancer therapy with an increase in efficiency by two orders ofmagnitude. Nanoscale 2021,13 (24), 10891-10897. (IF=6.7)
17. Zhang,Y.; Ding, Y.; Li, X.; Zheng, D.; Gao, J.*; Yang, Z.*, Supramolecularhydrogels of self-assembled zwitterionic-peptides. Chin. Chem.Lett.2021.32(11), 3636-3640. (IF=9.1)
18. Shang,Y.; Liu, H.; Peng, R.; Ren, C.; Luo, X.; Ma, C.; Gao, Y.; Wang, Z.; Gao, J.*;Liu, J.*; Yang, Z.*, PDGF-mimicking supramolecular nanofibers for ionizingradiation-induced injury repair. Chem. Eng. J. 2021,410, 128309. (IF=15.1)
19. Feng,K.; Ma, C.; Liu, Y.; Yang, X.; Yang, Z.; Chen, Y.; Xu, T.; Yang, C.; Zhang, S.; Li, Q.; Wei, Z.; Zhao, D.; Zeng,P.; Han, J.; Gao, J.*; Chen, Y.*; Duan, Y.*, Encapsulation of LXR ligandby D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removesLXR-induced lipogenesis. Theranostics 2021,11 (6), 2634-2654. (IF=12.4)
20. Liang,C.; Wang, Z.; Xu, T.; Chen, Y.; Zheng, D.; Zhang, L.; Zhang, W.; Yang, Z.; Shi,Y.*; Gao, J.*, Preorganization Increases the Self-Assembling Ability andAntitumor Efficacy of Peptide Nanomedicine. ACS Appl.Mater. Interfaces2020,12 (20), 22492-22498. (IF=9.5)
21. Gao,J.; Gu, Z.*, Toward nanoscopiccellular imaging by X-ray. Natl. Sci. Rev. 2020,nwaa206. (IF=20.7)
22. Shang,Y.; Liao, Y.; Ye, Z. J.; Wang, Z. Y.; Xiao, L.; Gao, J.*; Wang, Q.*;Yang, Z.*, Supramolecular protein glue to boost enzyme activity. Sci. ChinaMater.2019,62 (9), 1341-1349. (IF=8.1)
23. Shang,Y.; Zhi, D.; Feng, G.; Wang, Z.; Mao, D.; Guo, S.; Liu, R.; Liu, L.; Zhang, S.;Sun, S.; Wang, K.*; Kong, D.; Gao, J.*; Yang, Z.*, SupramolecularNanofibers with Superior Bioactivity to Insulin-Like Growth Factor-I. Nano Lett. 2019,19 (3), 1560-1569. (IF=10.8)
24. Gao,J.; Zhan, J.; Yang, Z.*,Enzyme-Instructed Self-Assembly (EISA) and Hydrogelation of Peptides. Adv. Mater. 2019,0 (0), 1805798. (IF=29.4)
25. Zhang,Y.; Pan, Y.-C.; Wang, Y.; Guo, D.-S.*; Gao, J.*; Yang, Z., Fastnaked-eye detection of zinc ions by molecular assembly-assisted polymerizationof diacetylene. Nanoscale 2018,10 (39), 18829-18834. (IF=6.7)
26. Li,H.#; Gao, J.#; Shang, Y.; Hua, Y.; Ye, M.; Yang,Z.*; Ou, C.*; Chen, M.*, Folic Acid Derived Hydrogel Enhances the Survival andPromotes Therapeutic Efficacy of iPS Cells for Acute Myocardial Infarction. ACS Appl.Mater. Interfaces2018,10 (29), 24459-24468. (#equalcontribution) (IF=9.5)
27. Zhan,J.; Cai, Y.; Ji, S.; Shang, Y.; Gao, J.*; Yang, Z.*, Supramolecular silkfrom a peptide hydrogel. Mater. Chem.Front. 2017, 1 (5), 911-915. (IF=7)
28. Wang,Z.; Cai, Y.; Yi, L.; Gao, J.*; Yang, Z.*, Supramolecular Hydrogels ofIndole-Capped Short Peptides as Vaccine Adjuvants. Chin. J. Chem.2017, 35 (7), 1057-1062. (IF=5.4)
29. Chen,G.; Li, J.; Song, M.; Wu, Z.; Zhang, W.; Wang, Z.; Gao, J.*; Yang, Z.*;Ou, C.*, A Mixed Component Supramolecular Hydrogel to Improve Mice CardiacFunction and Alleviate Ventricular Remodeling after Acute MyocardialInfarction. Adv. Funct.Mater. 2017, 27 (34), 1701798. (IF=19.0)
30. Cai,Y.; Shen, H.; Zhan, J.; Lin, M.; Dai, L.; Ren, C.; Shi, Y.; Liu, J.*; Gao,J.*; Yang, Z.*, Supramolecular “Trojan Horse” for Nuclear Delivery of DualAnticancer Drugs. J. Am. Chem.Soc. 2017, 139 (8), 4. (IF=15.0)
31. Wang,J.; Zheng, J.; Cai, Y.; Zheng, J.; Gao, J.*; Gong, Q.*; Yang, Z.*,Imaging cellular distribution of fluorescent supramolecular nanofibers. Sci. China Chem.2016, 59 (6), 719-723. (IF=9.6)
32. Xu,C.; Cai, Y.; Ren, C.; Gao, J.*; Hao, J.*, Zinc-Triggered Hydrogelationof Self-assembled Small Molecules to Inhibit Bacterial Growth. Sci. Rep.2015, 5. (IF=4.6)
33. Chen,G.; Chen, J.; Liu, Q.; Ou, C.*; Gao, J.*, Enzymatic formation of ameta-stable supramolecular hydrogel for 3D cell culture. RSC Adv.2015, 5 (39), 30675-30678. (IF=3.9)
34. Gao,J.;Shi, Y.; Wang, Y.; Cai, Y.; Shen, J.; Kong, D.*; Yang, Z.*, Enzyme-controllableF-NMR turn on through disassembly of peptide-based nanospheres for enzymedetection. Org. Biomol.Chem. 2014, 12 (9), 1383-1386. (IF=3.2)
35. Zheng,W.#; Gao, J.#; Song, L.; Chen, C.; Guan, D.; Wang,Z.; Li, Z.*; Kong, D.*; Yang, Z.*, Surface-Induced Hydrogelation InhibitsPlatelet Aggregation. J. Am. Chem.Soc. 2013, 135 (1), 266-271. (#equal contribution) (IF=15.0)
36. Gao,J.;Zheng, W.; Zhang, J.; Guan, D.; Yang, Z.*; Kong, D.; Zhao, Q.*,Enzyme-controllable delivery of nitric oxide from a molecular hydrogel. Chem. Commun.2013, 49 (80), 9173-9175. (IF=4.9)
37. Gao,J.;Zheng, W.; Kong, D.*; Yang, Z.*, Dual enzymes regulate the molecularself-assembly of tetra-peptide derivatives. Soft Matter2011, 7 (21), 10443-10448. (IF=3.4)
38. Gao,J.;Wang, H.; Wang, L.; Wang, J.; Kong, D.*; Yang, Z.*, Enzyme Promotes theHydrogelation from a Hydrophobic Small Molecule. J. Am. Chem. Soc.2009, 131 (32), 11286-11287. (IF=15.0)
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