承担国家以及天津市自然基金委项目若干

1.   Hou Jingli#,Pan Yiwa#,Zhu Dashuai#, Fan Yueyuan, Feng Guowei, Wei Yongzhen, Wang He, QinKang, Zhao Tiechan, Yang Qiang, Zhu Yan, Che Yongzhe, Liu Yangping, Cheng Jiansong*, Kong Deling, Wang PengGeorge, Shen Jie* and Zhao Qiang*, Targeted delivery of nitric oxide via a'bump-and-hole'-based enzyme-prodrug pair., Nature Chemical Biology, 2019.1,15(2): 151~160. (IF=13.8)

2.   Na Lu#, JinfengYe#, Jiansong Cheng#, AniruddhaSasmal, Chang-Cheng Liu, Wenlong Yao, Jun Yan, Naazneen Khan, Wen Yi, Ajit Varki, and Hongzhi Cao*, Redox-Controlled Site-Specific α2−6-Sialylation, J Am Chem Soc. 2019; 141(11):4547-4552. (IF=14.4)

3.  Zhang P, Liu P, Xu Y, Liang Y,Wang PG, Cheng J*. N-acetyltransferases from three different organismsdisplaying distinct selectivity toward hexosamines and N-terminal amine ofpeptides. Carbohydr Res. 2019;472:72-75.

4.   Xu Yangyang, Fan Yueyuan, YeJinfeng, Wang Faxing, Nie Quandeng, Wang Li, Wang Peng George*, Cao Hongzhi*, Cheng Jiansong*, Successfully Engineeringa Bacterial Sialyltransferase for Regioselective alpha 2,6-sialylation, ACSCatalysis, 2018.08, 8(8): 7222~7227. (IF=11.4)

5.   Xu Yangyang#, WuZhigang#, Zhang Peiru, Zhu He, Zhu Hailiang, Song Qitao, Wang Li,Wang Faxing, Wang Peng George* and ChengJiansong*, A novel enzymatic method for synthesis of glycopeptides carryingnatural eukaryotic N-glycans, CHEMICALCOMMUNICATIONS, 2017, 53(65): 9075~9077. (IF=6.3)

6.   Song Qitao#,WuZhigang#, Fan Yueyuan, Song Woran, Zhang Peiru, Wang Li, Wang Faxing,Xu Yangyang, Wang Peng G*. and Cheng,Jiansong*, Production of homogeneous glycoprotein with multisitemodifications by an engineered N-glycosyltransferase mutant, J BiolChem. 2017,292(21): 8856~8863. (IF=4.0)

7.   Song Q, Zhang X, Li N, Shen J, Cheng J*. A propeptide-independent protease from Tannerella sp.6_1_58FAA_CT1displays trypsin-like specificity. J Basic Microbiol. 2017; 57(1):50-56.

8.   Wu Z, Jiang K, Zhu H, Ma C, Yu Z, Li L, Guan W, LiuY, Zhu H, Chen Y, Li S, Li J, Cheng J, Zhang L, Wang PG.Site-DirectedGlycosylation of Peptide/Protein with Homogeneous O-Linked EukaryoticN-Glycans. Bioconjug Chem. 2016; 27(9):1972-5. (IF=4.5)

9.    Wang,Y., Jiang, K., Ma, H., Zeng, W., Wang, PG., Yao, N., Han, W., Cheng,J.*, Wang, W., Enzymatic production of HMO mimics by thesialylation of galacto-oligosaccharides. Food Chem. 2015, 181,51-6. (IF=4.9)

10. Wang W,Ma T, Zhang B, Yao N, Li M, Cui L, Li G, Ma Z, Cheng J.* A novelmechanism of protein thermostability: a unique N-terminal domain confers heatresistance to Fe/Mn-SODs. SciRep. 2014, 4:7284. (IF=4.1)

11.     Meng,X., Yao, W., Cheng, J., Zhang, X.,Jin, L., Yu, H., Chen, X., Wang, F., Cao, H., Regioselective chemoenzymaticsynthesis of ganglioside disialyl tetrasaccharide epitopes. J.Am. Chem. Soc., 2014, 136(14), 5205-8.(IF=14.4)

12.     Wang,L., Han, W., Xie, C., Hou, J., Fang, Q., Gu, J., Wang, PG., Cheng, J.*, Comparing the acceptor promiscuityof a Rosa hybrida glucosyltransferaseRhGT1 and an engineered microbial glucosyltransferase OleD(PSA) toward a smallflavonoid library. Carbohydr. Res., 2013, 368, 73-77.

13.     Han,W., Cai, L., Wu, B., Li, L., Xiao, Z., Cheng, J.*, Wang,P.G.. The wciN gene encodes an α-1,3-galactosyltransferase involved in thebiosynthesis of the capsule repeating unit of Streptococcus pneumoniae serotype 6B. ACS Biochemistry. 2012,51(29), 5804-10.

14.     ChenGY, Chen X, King S, Cavassani KA, Cheng J, Zheng X, Cao H, Yu H, Qu J,Fang D, Wu W, Bai XF, Liu JQ, Woodiga SA, Chen C, Sun L, Hogaboam CM, KunkelSL, Zheng P, Liu Y. Amelioration of sepsis by inhibiting sialidase-mediateddisruption of the CD24-SiglecG interaction.Nat Biotechnol.2011,29(5):428-35.

15.     Cheng,J.; Huang, S.; Yu, H.; Li, Y.; Lau, K.; Chen, X.Trans-sialidase activity of Photobacterium damsel a2,6-sialyltransferase and its application in the synthesisof sialosides. Glycobiology. 2010, 20(2), 1077-88.

16.     Yu, H.;Cheng, J.; Ding, L.; Khedri, Z.; Chen, Y.; Chin, S.; Lau,K.; Tiwari, V.; Chen, X. Chemoenzymatic synthesis of GD3 oligosaccharides andother disialyl glycans containing natural and non-natural sialic acids. JAm Chem Soc. 2009. 30;131(51),18467-77. (IF=14.4)

17.     Cheng,J.; Yu, H.; Lau, K.; Huang, S.; Chokhawala, H. A.; Li, Y.;Tiwari, V. K.; Chen, X. Multifunctionality of Campylobacterjejuni sialyltransferase CstII: Characterization of GD3/GT3oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidaseactivities. Glycobiology. 2008, 18,686-697.

18.     Feng,L.; Wang, W.; Cheng, J.; Ren, Y.; Zhao, G.; Gao, X.; Tang, Y.; Liu, X.;Han, W.; Peng, X.; Liu, R. and Wang, L. Genome and proteome of long-chainalkane degrading Geobacillus thermodenitrificans NG80-2 isolatedfrom a deep-subsurface oil reservoir. Proc. Natl.Acad. Sci. USA. 2007, 104, 5602-5607.